تداخل‌های دارویی
Drospirenone + Ivosidenib
شدت: شدید
Drospirenone and Ivosidenib: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Ivosidenib is a CYP3A4 inducer and may lower hormonal contraceptive exposure, including drospirenone, reducing contraceptive efficacy. The legacy direction is wrong.
معنای این تداخل به زبان ساده
Drospirenone and Ivosidenib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Drospirenone belongs to Endocrine; Ivosidenib belongs to Oncology.
چرا رخ می‌دهد
Ivosidenib induces CYP3A4, increasing the metabolism of drospirenone and lowering its concentrations.
اقدام لازم
Advise an additional or alternative non-hormonal contraceptive method during ivosidenib treatment and for a period after stopping.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Drospirenone و Ivosidenib، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Drospirenone
تداخلات دیگر Ivosidenib
پرسش‌های متداول
Can I take Drospirenone with Ivosidenib?
MediHelp rates the interaction as major. Drospirenone and Ivosidenib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ivosidenib is a CYP3A4 inducer and may lower hormonal contraceptive exposure, including drospirenone, reducing contraceptive efficacy. The legacy direction is wrong.
How serious is the interaction between Drospirenone and Ivosidenib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional or alternative non-hormonal contraceptive method during ivosidenib treatment and for a period after stopping.
What other medicines interact with Drospirenone?
MediHelp also lists interactions of Drospirenone with, for example, Belzutifan, Bosentan, Carbamazepine. The full list is on the Drospirenone page.
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مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
