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تداخل‌های دارویی

Elvitegravir / cobicistat / emtricitabine / tenofovir df + Lamivudine

شدت: منع مصرف

Elvitegravir / cobicistat / emtricitabine / tenofovir df and Lamivudine: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

This fixed-dose product already contains emtricitabine, which is closely related to lamivudine, so adding lamivudine duplicates the same cytosine analogue activity. This provides no added benefit, gives overlapping resistance selection, and raises the toxicity burden.

معنای این تداخل به زبان ساده

Elvitegravir / cobicistat / emtricitabine / tenofovir df and Lamivudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: High

چرا رخ می‌دهد

Therapeutic duplication: lamivudine and emtricitabine are both cytidine analogues sharing the same target and resistance pathway.

اقدام لازم

Do not combine; the single-tablet regimen is complete and should not be given with other antiretrovirals. Stop lamivudine if the regimen is used.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Elvitegravir / cobicistat / emtricitabine / tenofovir df و Lamivudine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Lamivudine?

MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Lamivudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This fixed-dose product already contains emtricitabine, which is closely related to lamivudine, so adding lamivudine duplicates the same cytosine analogue activity. This provides no added benefit, gives overlapping resistance selection, and raises the toxicity burden.

How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Lamivudine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; the single-tablet regimen is complete and should not be given with other antiretrovirals. Stop lamivudine if the regimen is used.

What other medicines interact with Lamivudine?

MediHelp also lists interactions of Lamivudine with, for example, Atidarsagene autotemcel, Betibeglogene autotemcel, Elivaldogene autotemcel. The full list is on the Lamivudine page.

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