تداخل‌های دارویی
Ethinyl estradiol-drospirenone + Exemestane
شدت: شدید
Ethinyl estradiol-drospirenone and Exemestane: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Exemestane works by lowering estrogen levels in postmenopausal women with hormone-sensitive breast cancer. Giving an estrogen-containing contraceptive at the same time supplies exogenous estrogen and can counteract the intended therapeutic effect. The pairing is also not appropriate in a patient with estrogen-dependent tumor.
معنای این تداخل به زبان ساده
Ethinyl estradiol-drospirenone and Exemestane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ethinyl estradiol-drospirenone belongs to Endocrine; Exemestane belongs to Oncology.
چرا رخ می‌دهد
Pharmacodynamic antagonism: exogenous ethinyl estradiol opposes the estrogen-lowering effect of aromatase inhibition.
اقدام لازم
Avoid concurrent use of estrogen-containing products with exemestane. Use a non-hormonal method if contraception is needed.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ethinyl estradiol-drospirenone و Exemestane، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant منع مصرف
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir منع مصرف
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir منع مصرف
- Ethinyl estradiol-drospirenone + Tranexamic acid منع مصرف
- Aminocaproic acid + Ethinyl estradiol-drospirenone شدید
- Amobarbital + Ethinyl estradiol-drospirenone شدید
تداخلات دیگر Exemestane
پرسش‌های متداول
Can I take Ethinyl estradiol-drospirenone with Exemestane?
MediHelp rates the interaction as major. Ethinyl estradiol-drospirenone and Exemestane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Exemestane works by lowering estrogen levels in postmenopausal women with hormone-sensitive breast cancer. Giving an estrogen-containing contraceptive at the same time supplies exogenous estrogen and can counteract the intended therapeutic effect. The pairing is also not appropriate in a patient with estrogen-dependent tumor.
How serious is the interaction between Ethinyl estradiol-drospirenone and Exemestane?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of estrogen-containing products with exemestane. Use a non-hormonal method if contraception is needed.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
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مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
