تداخل‌های دارویی
Ethinyl estradiol-levonorgestrel + Ombitasvir / paritaprevir / ritonavir and dasabuvir
شدت: منع مصرف
Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Coadministration of ethinyl estradiol-containing products with this HCV regimen has produced marked ALT elevations in clinical trials. The risk of liver injury makes the combination unsuitable. Ritonavir may also reduce contraceptive hormone exposure.
معنای این تداخل به زبان ساده
Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
The mechanism of the ALT elevation is not established; ritonavir may also alter estrogen metabolism.
اقدام لازم
Avoid ethinyl estradiol-containing contraceptives before and during this regimen. Switch to a progestin-only or non-hormonal method and restart estrogen only after the regimen has been completed, as advised in the labeling.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ethinyl estradiol-levonorgestrel و Ombitasvir / paritaprevir / ritonavir and dasabuvir، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ethinyl estradiol-levonorgestrel
- Ethinyl estradiol-levonorgestrel + Fezolinetant منع مصرف
- Ethinyl estradiol-levonorgestrel + Tranexamic acid منع مصرف
- Aminocaproic acid + Ethinyl estradiol-levonorgestrel شدید
- Amobarbital + Ethinyl estradiol-levonorgestrel شدید
- Anastrozole + Ethinyl estradiol-levonorgestrel شدید
- Antithrombin alfa + Ethinyl estradiol-levonorgestrel شدید
پرسش‌های متداول
Can I take Ethinyl estradiol-levonorgestrel with Ombitasvir / paritaprevir / ritonavir and dasabuvir?
MediHelp rates the interaction as contraindicated. Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Coadministration of ethinyl estradiol-containing products with this HCV regimen has produced marked ALT elevations in clinical trials. The risk of liver injury makes the combination unsuitable. Ritonavir may also reduce contraceptive hormone exposure.
How serious is the interaction between Ethinyl estradiol-levonorgestrel and Ombitasvir / paritaprevir / ritonavir and dasabuvir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ethinyl estradiol-containing contraceptives before and during this regimen. Switch to a progestin-only or non-hormonal method and restart estrogen only after the regimen has been completed, as advised in the labeling.
What other medicines interact with Ethinyl estradiol-levonorgestrel?
MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Tranexamic acid, Aminocaproic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
