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تداخل‌های دارویی

Fludrocortisone + Mifepristone

شدت: منع مصرف

Fludrocortisone and Mifepristone: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.

معنای این تداخل به زبان ساده

Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Fludrocortisone belongs to Endocrine; Mifepristone belongs to Endocrine.

سطح شواهد: Moderate

چرا رخ می‌دهد

Glucocorticoid receptor blockade reducing replacement efficacy

اقدام لازم

Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Fludrocortisone و Mifepristone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Fludrocortisone with Mifepristone?

MediHelp rates the interaction as contraindicated. Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.

How serious is the interaction between Fludrocortisone and Mifepristone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.

What other medicines interact with Fludrocortisone?

MediHelp also lists interactions of Fludrocortisone with, for example, Aldesleukin, Amphotericin b, Bcg vaccine live. The full list is on the Fludrocortisone page.

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