تداخل‌های دارویی
Glimepiride + Insulin glargine-lixisenatide
شدت: شدید
Glimepiride and Insulin glargine-lixisenatide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Glimepiride stimulates insulin secretion, so combining it with insulin and lixisenatide significantly raises the risk of hypoglycemia. The risk is greater in older patients, those with renal impairment and those with irregular meals.
معنای این تداخل به زبان ساده
Glimepiride and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Glimepiride belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
چرا رخ می‌دهد
Additive glucose lowering from sulfonylurea-driven insulin secretion plus exogenous insulin and GLP-1 receptor agonism.
اقدام لازم
Reduce the glimepiride dose when combining with this product and monitor glucose closely. Educate the patient on recognizing and treating hypoglycemia.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Glimepiride و Insulin glargine-lixisenatide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Insulin glargine-lixisenatide
تداخلات دیگر Glimepiride
پرسش‌های متداول
Can I take Glimepiride with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Glimepiride and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Glimepiride stimulates insulin secretion, so combining it with insulin and lixisenatide significantly raises the risk of hypoglycemia. The risk is greater in older patients, those with renal impairment and those with irregular meals.
How serious is the interaction between Glimepiride and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reduce the glimepiride dose when combining with this product and monitor glucose closely. Educate the patient on recognizing and treating hypoglycemia.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
