تداخل‌های دارویی
Influenza virus vaccine quadrivalent intranasal + Melphalan
شدت: منع مصرف
Influenza virus vaccine quadrivalent intranasal and Melphalan: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
The intranasal influenza vaccine contains live attenuated virus, which can replicate excessively in a patient immunosuppressed by melphalan. The vaccine response is also reduced.
معنای این تداخل به زبان ساده
Influenza virus vaccine quadrivalent intranasal and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
Chemotherapy-induced immunosuppression allows unchecked replication of live attenuated virus and impairs the vaccine response.
اقدام لازم
Use an inactivated injectable influenza vaccine instead during melphalan therapy. Avoid the live intranasal product until at least 3 months after treatment ends.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Influenza virus vaccine quadrivalent intranasal و Melphalan، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Melphalan
- Adenovirus types 4 and 7 live + Melphalan منع مصرف
- Bcg vaccine live + Melphalan منع مصرف
- Measles mumps and rubella vaccine live + Melphalan منع مصرف
- Measles mumps and rubella vaccine + Melphalan منع مصرف
- Measles mumps rubella and varicella vaccine live + Melphalan منع مصرف
- Measles vaccine + Melphalan منع مصرف
پرسش‌های متداول
Can I take Influenza virus vaccine quadrivalent intranasal with Melphalan?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which can replicate excessively in a patient immunosuppressed by melphalan. The vaccine response is also reduced.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Melphalan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use an inactivated injectable influenza vaccine instead during melphalan therapy. Avoid the live intranasal product until at least 3 months after treatment ends.
What other medicines interact with Melphalan?
MediHelp also lists interactions of Melphalan with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine live. The full list is on the Melphalan page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
