تداخل‌های دارویی
Interferon beta 1b + Pretomanid
شدت: شدید
Interferon beta 1b and Pretomanid: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
The pretomanid-containing regimen is associated with hepatotoxicity, and labeling advises avoiding other hepatotoxic agents. Interferon beta can raise transaminases and occasionally cause liver injury. Combining them may increase the risk of liver damage.
معنای این تداخل به زبان ساده
Interferon beta 1b and Pretomanid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Interferon beta 1b belongs to Central Nervous System; Pretomanid belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive hepatotoxicity from two agents that can each injure the liver.
اقدام لازم
Avoid concurrent use where possible and defer interferon beta during tuberculosis treatment. If unavoidable, monitor liver function tests regularly and stop the offending drugs if liver injury develops.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Interferon beta 1b و Pretomanid، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Interferon beta 1b
تداخلات دیگر Pretomanid
پرسش‌های متداول
Can I take Interferon beta 1b with Pretomanid?
MediHelp rates the interaction as major. Interferon beta 1b and Pretomanid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The pretomanid-containing regimen is associated with hepatotoxicity, and labeling advises avoiding other hepatotoxic agents. Interferon beta can raise transaminases and occasionally cause liver injury. Combining them may increase the risk of liver damage.
How serious is the interaction between Interferon beta 1b and Pretomanid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible and defer interferon beta during tuberculosis treatment. If unavoidable, monitor liver function tests regularly and stop the offending drugs if liver injury develops.
What other medicines interact with Interferon beta 1b?
MediHelp also lists interactions of Interferon beta 1b with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel. The full list is on the Interferon beta 1b page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
