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Meropenem + Sodium picosulfate / magnesium oxide / anhydrous citric acid

شدت: متوسط

Meropenem and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Sodium picosulfate is a prodrug that needs colonic bacteria to convert it into its active laxative form. A broad-spectrum carbapenem such as meropenem can suppress colonic flora and may reduce the bowel-cleansing effect before colonoscopy.

معنای این تداخل به زبان ساده

Meropenem and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Low

چرا رخ می‌دهد

Antibiotic-induced reduction of colonic bacteria impairs conversion of sodium picosulfate to its active metabolite.

اقدام لازم

Watch for inadequate bowel preparation in patients on the antibiotic and consider extra preparation or rescheduling if cleansing is poor. Where possible, avoid starting the antibiotic during the preparation window.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Meropenem و Sodium picosulfate / magnesium oxide / anhydrous citric acid، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Meropenem with Sodium picosulfate / magnesium oxide / anhydrous citric acid?

MediHelp rates the interaction as moderate. Meropenem and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that needs colonic bacteria to convert it into its active laxative form. A broad-spectrum carbapenem such as meropenem can suppress colonic flora and may reduce the bowel-cleansing effect before colonoscopy.

How serious is the interaction between Meropenem and Sodium picosulfate / magnesium oxide / anhydrous citric acid?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Watch for inadequate bowel preparation in patients on the antibiotic and consider extra preparation or rescheduling if cleansing is poor. Where possible, avoid starting the antibiotic during the preparation window.

What other medicines interact with Meropenem?

MediHelp also lists interactions of Meropenem with, for example, Valproic acid, Typhoid vaccine live, Amifampridine. The full list is on the Meropenem page.

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