تداخل‌های دارویی
Scopolamine + Trihexyphenidyl
شدت: شدید
Scopolamine and Trihexyphenidyl: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Both are potent antimuscarinics, so combining them can produce marked anticholinergic toxicity with dry mouth, constipation, urinary retention, blurred vision, tachycardia, confusion and hallucinations. Older adults are especially susceptible, and hyperthermia can occur.
معنای این تداخل به زبان ساده
Scopolamine and Trihexyphenidyl can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Scopolamine belongs to Respiratory; Trihexyphenidyl belongs to Central Nervous System.
چرا رخ می‌دهد
Additive muscarinic receptor blockade in the central and peripheral nervous systems.
اقدام لازم
Avoid the combination where possible, particularly in older adults. If it is necessary, use the lowest doses and monitor for delirium, retention and tachycardia.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Scopolamine و Trihexyphenidyl، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Scopolamine
تداخلات دیگر Trihexyphenidyl
پرسش‌های متداول
Can I take Scopolamine with Trihexyphenidyl?
MediHelp rates the interaction as major. Scopolamine and Trihexyphenidyl can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are potent antimuscarinics, so combining them can produce marked anticholinergic toxicity with dry mouth, constipation, urinary retention, blurred vision, tachycardia, confusion and hallucinations. Older adults are especially susceptible, and hyperthermia can occur.
How serious is the interaction between Scopolamine and Trihexyphenidyl?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, particularly in older adults. If it is necessary, use the lowest doses and monitor for delirium, retention and tachycardia.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
