تداخل‌های دارویی
Tranexamic acid + Tretinoin
شدت: شدید
Tranexamic acid and Tretinoin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Tranexamic acid is antifibrinolytic and oral tretinoin used for acute promyelocytic leukaemia is associated with thrombotic events. Together they may add to the risk of thrombosis, and some labeling advises caution. The concern is chiefly with systemic tretinoin.
معنای این تداخل به زبان ساده
Tranexamic acid and Tretinoin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Tranexamic acid belongs to Cardiovascular; Tretinoin belongs to Dermatology.
چرا رخ می‌دهد
Additive prothrombotic effects: tranexamic acid inhibits fibrinolysis while tretinoin is associated with a procoagulant state.
اقدام لازم
Avoid the combination where possible, particularly in acute promyelocytic leukaemia with coagulopathy. If it is necessary, monitor for signs of venous or arterial thrombosis and coagulation parameters.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Tranexamic acid و Tretinoin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Tranexamic acid
- Dienogest / estradiol valerate + Tranexamic acid منع مصرف
- Ethinyl estradiol-drospirenone + Tranexamic acid منع مصرف
- Ethinyl estradiol-levonorgestrel + Tranexamic acid منع مصرف
- Ethinyl estradiol-norgestimate + Tranexamic acid منع مصرف
- Ethinylestradiol + Tranexamic acid منع مصرف
- Mestranol + Tranexamic acid منع مصرف
تداخلات دیگر Tretinoin
پرسش‌های متداول
Can I take Tranexamic acid with Tretinoin?
MediHelp rates the interaction as major. Tranexamic acid and Tretinoin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Tranexamic acid is antifibrinolytic and oral tretinoin used for acute promyelocytic leukaemia is associated with thrombotic events. Together they may add to the risk of thrombosis, and some labeling advises caution. The concern is chiefly with systemic tretinoin.
How serious is the interaction between Tranexamic acid and Tretinoin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, particularly in acute promyelocytic leukaemia with coagulopathy. If it is necessary, monitor for signs of venous or arterial thrombosis and coagulation parameters.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
