Référentiel des médicaments
Deucravacitinib
Deucravacitinib is a medicine in the class miscellaneous. It is used for plaque psoriasis.
- Classe médicamenteuse: Miscellaneous
- Indications: plaque psoriasis
Dernière mise à jour Sources: US FDA label
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
L'essentiel
- Classe médicamenteuse
- Miscellaneous
- Code ATC
- L04AF07
- Formes courantes
- comprimé
- Dosages courants
- 6 mg
- Noms commerciaux
- 2
- Pays et marchés
- 2
Indications
Mécanisme d'action
Allosteric inhibitor of tyrosine kinase 2 (TYK2); binds the regulatory domain, stabilizing an inhibitory interaction with the catalytic domain and inhibiting receptor-mediated TYK2 activation and downstream STAT activation.
Posologie adulte habituelle (résumé de la notice)
Plaque psoriasis and psoriatic arthritis: 6 mg orally once daily, with or without food
Grossesse et allaitement
- Grossesse
- Unknown Case reports are too few to assess risk; no embryo-fetal effects in rats and rabbits at doses at least 72 times the maximum human dose. Use only if the benefit justifies the risk.
- Allaitement
- Unknown No human milk data; it is present in rat milk. US label: weigh breastfeeding against the mother's need. No guidance supports routine use; an alternative with more data may be preferred.
Effets indésirables signalés
- Upper respiratory infections
- Blood creatine phosphokinase increased
- Herpes simplex
- Mouth ulcers
- Folliculitis
- Acne
Contre-indications
- History of hypersensitivity reaction to deucravacitinib or any excipients.
Précautions particulières
- Hypersensitivity reactions such as angioedema have been reported; discontinue if clinically significant reaction occurs.
- May increase risk of infections; avoid in active or serious infection; herpes virus reactivation reported; consider hepatitis screening.
- Evaluate for latent and active TB before starting; do not give to patients with active TB.
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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Lectures rapides associées
Questions fréquentes
What is Deucravacitinib used for?
Deucravacitinib is a medicine in the class miscellaneous. It is used for Plaque psoriasis, Psoriatic arthritis.
What side effects have been reported with Deucravacitinib?
Upper respiratory infections, Blood creatine phosphokinase increased, Herpes simplex, Mouth ulcers, Folliculitis, Acne.
Can Deucravacitinib be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Case reports are too few to assess risk; no embryo-fetal effects in rats and rabbits at doses at least 72 times the maximum human dose. Use only if the benefit justifies the risk. Breastfeeding: Unknown. No human milk data; it is present in rat milk. US label: weigh breastfeeding against the mother's need. No guidance supports routine use; an alternative with more data may be preferred.
What does Deucravacitinib interact with?
MediHelp does not list a checked interaction for Deucravacitinib yet. Always tell your pharmacist about every medicine you take.
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