Référentiel des médicaments
Itopride
Itopride is a medicine in the class gastrointestinal tract. It is used for dyspepsia.
- Classe médicamenteuse: Gastrointestinal Tract
- Indications: dyspepsia
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L'essentiel
- Classe médicamenteuse
- Gastrointestinal Tract
- Formes courantes
- comprimé
- Dosages courants
- 50 mg
- Noms commerciaux
- 16
- Pays et marchés
- 4
Indications
Mécanisme d'action
Itopride hydrochloride activates gastrointestinal propulsive motility due to its dopamine D2 antagonizing activity and acetylcholinesterase inhibitory activity. Itopride activates acetylcholine release and inhibits degradation.
Posologie adulte habituelle (résumé de la notice)
Recommended Dose: 50 mg daily (150-mg tab taken orally 3 times a day before meals).
Grossesse et allaitement
- Grossesse
- Unknown Prokinetic for indigestion; not FDA-approved. Human data are lacking or limited. Irish label: use in pregnancy only if the benefits clearly outweigh the risks. Better-studied options (e.g. metoclopramide for nausea) are usually preferred.
- Allaitement
- Unknown No human data; it passes into rat milk. Irish label: decide whether to stop breastfeeding or avoid itopride; some national labels advise not breastfeeding during treatment. Domperidone or metoclopramide have more lactation data.
Effets indésirables signalés
- Diarrhea
- Abdominal pain
- Gynacomastia (Rare)
- Jaundice (Rare)
Contre-indications
- Hypersensitivity to itopride or to any of the excipients.
- Patients in whom increased gastrointestinal motility could be harmful, such as those with gastrointestinal haemorrhage, mechanical obstruction or perforation.
Précautions particulières
- Itopride enhances the action of acetylcholine and may cause cholinergic adverse effects; use with caution.
- Do not continue treatment for a prolonged period if symptoms of functional dyspepsia do not improve; reassess the patient.
- Hepatic dysfunction and jaundice with raised AST, ALT and gamma-GT have been reported; monitor and stop treatment if abnormalities occur.
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Questions fréquentes
What is Itopride used for?
Itopride is a medicine in the class gastrointestinal tract. It is used for Dyspepsia, Gastrointestinal dysmotility, Gastroparesis, Nausea & vomiting.
What side effects have been reported with Itopride?
Diarrhea, Abdominal pain, Gynacomastia (Rare), Jaundice (Rare).
Can Itopride be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Prokinetic for indigestion; not FDA-approved. Human data are lacking or limited. Irish label: use in pregnancy only if the benefits clearly outweigh the risks. Better-studied options (e.g. metoclopramide for nausea) are usually preferred. Breastfeeding: Unknown. No human data; it passes into rat milk. Irish label: decide whether to stop breastfeeding or avoid itopride; some national labels advise not breastfeeding during treatment. Domperidone or metoclopramide have more lactation data.
What does Itopride interact with?
MediHelp does not list a checked interaction for Itopride yet. Always tell your pharmacist about every medicine you take.
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