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Interactions médicamenteuses

Acetaminophen / phenyltoloxamine + Levetiracetam

Gravité: Modérée

Acetaminophen / phenyltoloxamine and Levetiracetam: moderate interaction.

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Résumé

Phenyltoloxamine is a sedating first-generation antihistamine, and levetiracetam also causes somnolence and dizziness. Together they may increase drowsiness and impair psychomotor performance.

Ce que signifie cette interaction, en termes simples

Acetaminophen / phenyltoloxamine and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive CNS depression from the sedating antihistamine and levetiracetam.

Conduite à tenir

Warn patients about drowsiness and avoid driving or hazardous tasks until the response is known. Avoid alcohol and consider a non-sedating alternative.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Acetaminophen / phenyltoloxamine with Levetiracetam?

MediHelp rates the interaction as moderate. Acetaminophen / phenyltoloxamine and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phenyltoloxamine is a sedating first-generation antihistamine, and levetiracetam also causes somnolence and dizziness. Together they may increase drowsiness and impair psychomotor performance.

How serious is the interaction between Acetaminophen / phenyltoloxamine and Levetiracetam?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn patients about drowsiness and avoid driving or hazardous tasks until the response is known. Avoid alcohol and consider a non-sedating alternative.

What other medicines interact with Levetiracetam?

MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.

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