Aller au contenu

Interactions médicamenteuses

Levetiracetam + Oliceridine

Gravité: Majeure

Levetiracetam and Oliceridine: major interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Oliceridine is an opioid and its sedative and respiratory depressant effects may be potentiated by other CNS depressants. Levetiracetam adds to somnolence, so profound sedation is possible.

Ce que signifie cette interaction, en termes simples

Levetiracetam and Oliceridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Levetiracetam belongs to Central Nervous System; Oliceridine belongs to Musculoskeletal.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive central nervous system and respiratory depression (pharmacodynamic).

Conduite à tenir

Use the lowest effective oliceridine dose and monitor sedation level and respiratory rate. Reduce the opioid dose if excessive sedation occurs.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Levetiracetam et Oliceridine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Levetiracetam with Oliceridine?

MediHelp rates the interaction as major. Levetiracetam and Oliceridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oliceridine is an opioid and its sedative and respiratory depressant effects may be potentiated by other CNS depressants. Levetiracetam adds to somnolence, so profound sedation is possible.

How serious is the interaction between Levetiracetam and Oliceridine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective oliceridine dose and monitor sedation level and respiratory rate. Reduce the opioid dose if excessive sedation occurs.

What other medicines interact with Levetiracetam?

MediHelp also lists interactions of Levetiracetam with, for example, Opium tincture, Sodium oxybate, Sufentanil. The full list is on the Levetiracetam page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter