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Interactions médicamenteuses

Aclidinium + Atropine

Gravité: Modérée

Aclidinium and Atropine: moderate interaction.

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Résumé

Both are antimuscarinic agents, so using them together adds to anticholinergic effects. Patients may develop dry mouth, constipation, urinary retention, tachycardia, blurred vision or raised intraocular pressure.

Ce que signifie cette interaction, en termes simples

Aclidinium and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive muscarinic receptor antagonism.

Conduite à tenir

Avoid routine concurrent use of inhaled aclidinium with other antimuscarinics where possible. Monitor for urinary retention, glaucoma symptoms and constipation, and stop one agent if anticholinergic toxicity appears.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Aclidinium with Atropine?

MediHelp rates the interaction as moderate. Aclidinium and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinic agents, so using them together adds to anticholinergic effects. Patients may develop dry mouth, constipation, urinary retention, tachycardia, blurred vision or raised intraocular pressure.

How serious is the interaction between Aclidinium and Atropine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use of inhaled aclidinium with other antimuscarinics where possible. Monitor for urinary retention, glaucoma symptoms and constipation, and stop one agent if anticholinergic toxicity appears.

What other medicines interact with Atropine?

MediHelp also lists interactions of Atropine with, for example, Eluxadoline, Henbane, Pramlintide. The full list is on the Atropine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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