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Interactions médicamenteuses

Amantadine + Atropine

Gravité: Modérée

Amantadine and Atropine: moderate interaction.

Dernière mise à jour

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Résumé

Amantadine has anticholinergic properties, and atropine is a potent antimuscarinic. Together they may increase dry mouth, blurred vision, constipation, urinary retention, tachycardia and confusion, particularly in older adults.

Ce que signifie cette interaction, en termes simples

Amantadine and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amantadine belongs to Anti Virals; Atropine belongs to Miscellaneous.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive anticholinergic effects (pharmacodynamic).

Conduite à tenir

Monitor for anticholinergic effects and mental status changes, especially in elderly patients. Reduce the dose of one agent if adverse effects develop.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Amantadine with Atropine?

MediHelp rates the interaction as moderate. Amantadine and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amantadine has anticholinergic properties, and atropine is a potent antimuscarinic. Together they may increase dry mouth, blurred vision, constipation, urinary retention, tachycardia and confusion, particularly in older adults.

How serious is the interaction between Amantadine and Atropine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and mental status changes, especially in elderly patients. Reduce the dose of one agent if adverse effects develop.

What other medicines interact with Amantadine?

MediHelp also lists interactions of Amantadine with, for example, Ethanol, Memantine-donepezil, Metoclopramide. The full list is on the Amantadine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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