Interactions médicamenteuses
Adenovirus types 4 and 7 live + Etoposide
Gravité: Contre-indiquée
Adenovirus types 4 and 7 live and Etoposide: contraindicated interaction.
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Résumé
Etoposide causes immunosuppression, so a live adenovirus vaccine may cause uncontrolled vaccine-virus replication and disease. The vaccine response may also be inadequate.
Ce que signifie cette interaction, en termes simples
Adenovirus types 4 and 7 live and Etoposide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Chemotherapy-induced immunosuppression impairs control of live attenuated virus and reduces vaccine immunogenicity.
Conduite à tenir
Do not give the live vaccine during etoposide therapy; wait at least 3 months after chemotherapy ends and until immune recovery.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Etoposide
- Etoposide + Pentostatin Contre-indiquée
- Cyclosporine + Etoposide Majeure
- Cyclosporin + Etoposide Majeure
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Etoposide Majeure
- Etoposide + Fingolimod Majeure
- Etoposide + Fosphenytoin Majeure
Questions fréquentes
Can I take Adenovirus types 4 and 7 live with Etoposide?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Etoposide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Etoposide causes immunosuppression, so a live adenovirus vaccine may cause uncontrolled vaccine-virus replication and disease. The vaccine response may also be inadequate.
How serious is the interaction between Adenovirus types 4 and 7 live and Etoposide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during etoposide therapy; wait at least 3 months after chemotherapy ends and until immune recovery.
What other medicines interact with Etoposide?
MediHelp also lists interactions of Etoposide with, for example, Pentostatin, Cyclosporine, Cyclosporin. The full list is on the Etoposide page.
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