Interactions médicamenteuses
Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin
Gravité: Majeure
Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin: major interaction.
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Résumé
Topical antibiotics applied to a wound can degrade or damage the living cultured cell construct. This may reduce the graft's viability and therapeutic effect.
Ce que signifie cette interaction, en termes simples
Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Direct cytotoxic effect of topical antibiotics on the cultured cells at the wound site.
Conduite à tenir
Do not apply the antibiotic ointment to the site before the graft. If exposed, irrigate the wound thoroughly with saline and allow a washout period before application.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Bacitracin-neomycin-polymyxin
- Atracurium + Bacitracin-neomycin-polymyxin Majeure
- Bacitracin-neomycin-polymyxin + Capreomycin Majeure
- Bacitracin-neomycin-polymyxin + Cidofovir Majeure
- Bacitracin-neomycin-polymyxin + Cisatracurium Majeure
- Bacitracin-neomycin-polymyxin + Pancuronium Majeure
- Bacitracin-neomycin-polymyxin + Rocuronium Majeure
Questions fréquentes
Can I take Allogeneic cultured keratinocytes / fibroblasts in bovine collagen with Bacitracin-neomycin-polymyxin?
MediHelp rates the interaction as major. Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Topical antibiotics applied to a wound can degrade or damage the living cultured cell construct. This may reduce the graft's viability and therapeutic effect.
How serious is the interaction between Allogeneic cultured keratinocytes / fibroblasts in bovine collagen and Bacitracin-neomycin-polymyxin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not apply the antibiotic ointment to the site before the graft. If exposed, irrigate the wound thoroughly with saline and allow a washout period before application.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Atracurium, Capreomycin, Cidofovir. The full list is on the Bacitracin-neomycin-polymyxin page.
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