Interactions médicamenteuses
Alogliptin-pioglitazone + Lonapegsomatropin
Gravité: Modérée
Alogliptin-pioglitazone and Lonapegsomatropin: moderate interaction.
Dernière mise à jour
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Résumé
Growth hormone reduces insulin sensitivity, which can raise blood glucose and blunt the effect of alogliptin and pioglitazone. Patients with diabetes may need higher doses of their antihyperglycemic agents.
Ce que signifie cette interaction, en termes simples
Alogliptin-pioglitazone and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Lonapegsomatropin belongs to Endocrine.
Pourquoi elle survient
Pharmacodynamic antagonism through growth hormone-induced insulin resistance.
Conduite à tenir
Monitor blood glucose and HbA1c when starting or adjusting lonapegsomatropin. Adjust antidiabetic doses as required.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Alogliptin-pioglitazone
Autres interactions de Lonapegsomatropin
Questions fréquentes
Can I take Alogliptin-pioglitazone with Lonapegsomatropin?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone reduces insulin sensitivity, which can raise blood glucose and blunt the effect of alogliptin and pioglitazone. Patients with diabetes may need higher doses of their antihyperglycemic agents.
How serious is the interaction between Alogliptin-pioglitazone and Lonapegsomatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when starting or adjusting lonapegsomatropin. Adjust antidiabetic doses as required.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.