Interactions médicamenteuses
Alogliptin-metformin + Lonapegsomatropin
Gravité: Modérée
Alogliptin-metformin and Lonapegsomatropin: moderate interaction.
Dernière mise à jour
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Résumé
Growth hormone can reduce insulin sensitivity and raise blood glucose, which may weaken the effect of alogliptin and metformin. Patients with diabetes may need their antidiabetic therapy adjusted when it is started or the dose increased.
Ce que signifie cette interaction, en termes simples
Alogliptin-metformin and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-metformin belongs to Endocrine; Lonapegsomatropin belongs to Endocrine.
Pourquoi elle survient
Growth hormone induces insulin resistance and counteracts the glucose-lowering effect of antidiabetic drugs (pharmacodynamic antagonism).
Conduite à tenir
Monitor blood glucose and HbA1c after starting or changing the dose of lonapegsomatropin. Increase antihyperglycemic therapy as needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Alogliptin-metformin
Autres interactions de Lonapegsomatropin
Questions fréquentes
Can I take Alogliptin-metformin with Lonapegsomatropin?
MediHelp rates the interaction as moderate. Alogliptin-metformin and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone can reduce insulin sensitivity and raise blood glucose, which may weaken the effect of alogliptin and metformin. Patients with diabetes may need their antidiabetic therapy adjusted when it is started or the dose increased.
How serious is the interaction between Alogliptin-metformin and Lonapegsomatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting or changing the dose of lonapegsomatropin. Increase antihyperglycemic therapy as needed.
What other medicines interact with Alogliptin-metformin?
MediHelp also lists interactions of Alogliptin-metformin with, for example, Clozapine, Contrast media, Diatrizoate. The full list is on the Alogliptin-metformin page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
