Interactions médicamenteuses
Alogliptin-pioglitazone + Somatrogon
Gravité: Modérée
Alogliptin-pioglitazone and Somatrogon: moderate interaction.
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Résumé
Somatrogon, a long-acting growth hormone, can lower insulin sensitivity and raise blood glucose, reducing the efficacy of antidiabetic drugs. Patients with diabetes may need treatment intensification.
Ce que signifie cette interaction, en termes simples
Alogliptin-pioglitazone and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Somatrogon belongs to Endocrine.
Pourquoi elle survient
Growth hormone induces insulin resistance, opposing the glucose-lowering effect of pioglitazone and alogliptin.
Conduite à tenir
Monitor blood glucose and HbA1c when somatrogon is started or the dose changed, and adjust antidiabetic doses accordingly.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Alogliptin-pioglitazone
Autres interactions de Somatrogon
- Alogliptin-metformin + Somatrogon Modérée
- Alogliptin + Somatrogon Modérée
- Canagliflozin-metformin + Somatrogon Modérée
- Chlorpropamide + Somatrogon Modérée
- Cyclosporin + Somatrogon Modérée
- Dapagliflozin-metformin + Somatrogon Modérée
Questions fréquentes
Can I take Alogliptin-pioglitazone with Somatrogon?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatrogon, a long-acting growth hormone, can lower insulin sensitivity and raise blood glucose, reducing the efficacy of antidiabetic drugs. Patients with diabetes may need treatment intensification.
How serious is the interaction between Alogliptin-pioglitazone and Somatrogon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when somatrogon is started or the dose changed, and adjust antidiabetic doses accordingly.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
