Interactions médicamenteuses
Alprazolam + Gabapentin
Gravité: Majeure
Alprazolam and Gabapentin: major interaction.
Dernière mise à jour
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Résumé
Gabapentin combined with alprazolam causes additive sedation and psychomotor impairment. Respiratory depression may occur, especially in older patients, those with lung disease, or at high doses.
Ce que signifie cette interaction, en termes simples
Alprazolam and Gabapentin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Alprazolam belongs to Central Nervous System; Gabapentin belongs to Central Nervous System.
Pourquoi elle survient
Additive pharmacodynamic CNS and respiratory depression.
Conduite à tenir
Use the lowest effective doses and monitor for sedation and respiratory depression, particularly at initiation and dose increases. Counsel on alcohol and driving.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Alprazolam
- Alprazolam + Calcium / magnesium / potassium / sodium oxybates Contre-indiquée
- Alprazolam + Itraconazole Contre-indiquée
- Alprazolam + Ketoconazole Contre-indiquée
- Alprazolam + Levoketoconazole Contre-indiquée
- Alprazolam + Sodium oxybate Contre-indiquée
- Alfentanil + Alprazolam Majeure
Autres interactions de Gabapentin
Questions fréquentes
Can I take Alprazolam with Gabapentin?
MediHelp rates the interaction as major. Alprazolam and Gabapentin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Gabapentin combined with alprazolam causes additive sedation and psychomotor impairment. Respiratory depression may occur, especially in older patients, those with lung disease, or at high doses.
How serious is the interaction between Alprazolam and Gabapentin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor for sedation and respiratory depression, particularly at initiation and dose increases. Counsel on alcohol and driving.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
