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Interactions médicamenteuses

Anakinra + Measles vaccine

Gravité: Contre-indiquée

Anakinra and Measles vaccine: contraindicated interaction.

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Résumé

Measles vaccine is live attenuated and may cause vaccine-strain disease in patients on immunosuppressive therapy such as anakinra. The immune response may also be inadequate.

Ce que signifie cette interaction, en termes simples

Anakinra and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Low

Pourquoi elle survient

Immunosuppression permits uncontrolled replication of the live attenuated virus.

Conduite à tenir

Avoid live measles vaccine during anakinra therapy; vaccinate before starting treatment or defer until therapy is stopped, and consider immunoglobulin after exposure.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anakinra with Measles vaccine?

MediHelp rates the interaction as contraindicated. Anakinra and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated and may cause vaccine-strain disease in patients on immunosuppressive therapy such as anakinra. The immune response may also be inadequate.

How serious is the interaction between Anakinra and Measles vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live measles vaccine during anakinra therapy; vaccinate before starting treatment or defer until therapy is stopped, and consider immunoglobulin after exposure.

What other medicines interact with Anakinra?

MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.

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