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Interactions médicamenteuses

Anakinra + Measles mumps and rubella vaccine

Gravité: Contre-indiquée

Anakinra and Measles mumps and rubella vaccine: contraindicated interaction.

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Résumé

The live-attenuated MMR-containing vaccine can replicate unchecked in a patient immunosuppressed by anakinra. This may cause disseminated vaccine-strain disease.

Ce que signifie cette interaction, en termes simples

Anakinra and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Anakinra belongs to Musculoskeletal; Measles mumps and rubella vaccine belongs to Miscellaneous.

Niveau de preuve: High

Pourquoi elle survient

Immunosuppression permits uncontrolled replication of live vaccine virus

Conduite à tenir

Do not give live vaccines during therapy; complete immunisation at least 4 weeks before starting, or defer until after the drug has cleared.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anakinra with Measles mumps and rubella vaccine?

MediHelp rates the interaction as contraindicated. Anakinra and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live-attenuated MMR-containing vaccine can replicate unchecked in a patient immunosuppressed by anakinra. This may cause disseminated vaccine-strain disease.

How serious is the interaction between Anakinra and Measles mumps and rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during therapy; complete immunisation at least 4 weeks before starting, or defer until after the drug has cleared.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Antithymocyte globulin equine, Antithymocyte globulin rabbit. The full list is on the Measles mumps and rubella vaccine page.

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