Interactions médicamenteuses
Antithrombin alfa + Piperacillin
Gravité: Modérée
Antithrombin alfa and Piperacillin: moderate interaction.
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Résumé
Piperacillin can impair platelet function and may add to bleeding risk in patients receiving antithrombin, which is used with heparin. The interaction is mainly theoretical and may be modest.
Ce que signifie cette interaction, en termes simples
Antithrombin alfa and Piperacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
High-dose piperacillin impairs platelet aggregation, adding to antithrombin-enhanced anticoagulation.
Conduite à tenir
Monitor for bleeding and coagulation parameters such as aPTT or anti-Xa during co-therapy.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Piperacillin
- Piperacillin + Vancomycin Majeure
- Acetylsalicylic acid + Piperacillin Modérée
- Amikacin + Piperacillin Modérée
- Antithrombin iii + Piperacillin Modérée
- Argatroban + Piperacillin Modérée
- Avelumab + Piperacillin Modérée
Questions fréquentes
Can I take Antithrombin alfa with Piperacillin?
MediHelp rates the interaction as moderate. Antithrombin alfa and Piperacillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Piperacillin can impair platelet function and may add to bleeding risk in patients receiving antithrombin, which is used with heparin. The interaction is mainly theoretical and may be modest.
How serious is the interaction between Antithrombin alfa and Piperacillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and coagulation parameters such as aPTT or anti-Xa during co-therapy.
What other medicines interact with Piperacillin?
MediHelp also lists interactions of Piperacillin with, for example, Vancomycin, Acetylsalicylic acid, Amikacin. The full list is on the Piperacillin page.
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