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Interactions médicamenteuses

Antithymocyte globulin equine + Hepatitis A vaccine inactivated

Gravité: Modérée

Antithymocyte globulin equine and Hepatitis A vaccine inactivated: moderate interaction.

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Résumé

Antithymocyte globulin depletes T cells and may substantially reduce the response to inactivated hepatitis A vaccine. Since the vaccine is non-replicating, it is safe but may be ineffective.

Ce que signifie cette interaction, en termes simples

Antithymocyte globulin equine and Hepatitis A vaccine inactivated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Profound T-cell depletion impairs the T-cell-dependent antibody response to vaccination.

Conduite à tenir

Delay non-urgent vaccination until immune reconstitution; if given, check serologic response and revaccinate if needed.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Antithymocyte globulin equine with Hepatitis A vaccine inactivated?

MediHelp rates the interaction as moderate. Antithymocyte globulin equine and Hepatitis A vaccine inactivated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antithymocyte globulin depletes T cells and may substantially reduce the response to inactivated hepatitis A vaccine. Since the vaccine is non-replicating, it is safe but may be ineffective.

How serious is the interaction between Antithymocyte globulin equine and Hepatitis A vaccine inactivated?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Delay non-urgent vaccination until immune reconstitution; if given, check serologic response and revaccinate if needed.

What other medicines interact with Hepatitis A vaccine inactivated?

MediHelp also lists interactions of Hepatitis A vaccine inactivated with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Hepatitis A vaccine inactivated page.

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