Interactions médicamenteuses
Atidarsagene autotemcel + Hepatitis A vaccine inactivated
Gravité: Modérée
Atidarsagene autotemcel and Hepatitis A vaccine inactivated: moderate interaction.
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Résumé
Atidarsagene autotemcel is a gene therapy given after myeloablative conditioning, leaving patients with a temporarily absent or recovering immune system. Vaccines given around this period may be ineffective, and their safety has not been studied.
Ce que signifie cette interaction, en termes simples
Atidarsagene autotemcel and Hepatitis A vaccine inactivated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atidarsagene autotemcel belongs to Miscellaneous; Hepatitis A vaccine inactivated belongs to Anti Virals.
Pourquoi elle survient
Pharmacodynamic: myeloablative conditioning and hematologic reconstitution impair the immune response to vaccination.
Conduite à tenir
Give vaccines, where feasible, before myeloablative conditioning and avoid vaccination in the 6 weeks before conditioning. Postpone further vaccination until hematologic recovery, then revaccinate as needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Hepatitis A vaccine inactivated
- Adalimumab + Hepatitis A vaccine inactivated Modérée
- Alefacept + Hepatitis A vaccine inactivated Modérée
- Anakinra + Hepatitis A vaccine inactivated Modérée
- Anti-thymocyte + Hepatitis A vaccine inactivated Modérée
- Antithymocyte globulin equine + Hepatitis A vaccine inactivated Modérée
- Antithymocyte globulin rabbit + Hepatitis A vaccine inactivated Modérée
Autres interactions de Atidarsagene autotemcel
Questions fréquentes
Can I take Atidarsagene autotemcel with Hepatitis A vaccine inactivated?
MediHelp rates the interaction as moderate. Atidarsagene autotemcel and Hepatitis A vaccine inactivated can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atidarsagene autotemcel is a gene therapy given after myeloablative conditioning, leaving patients with a temporarily absent or recovering immune system. Vaccines given around this period may be ineffective, and their safety has not been studied.
How serious is the interaction between Atidarsagene autotemcel and Hepatitis A vaccine inactivated?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give vaccines, where feasible, before myeloablative conditioning and avoid vaccination in the 6 weeks before conditioning. Postpone further vaccination until hematologic recovery, then revaccinate as needed.
What other medicines interact with Hepatitis A vaccine inactivated?
MediHelp also lists interactions of Hepatitis A vaccine inactivated with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Hepatitis A vaccine inactivated page.
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