Interactions médicamenteuses
Antithymocyte globulin rabbit + Echinacea
Gravité: Modérée
Antithymocyte globulin rabbit and Echinacea: moderate interaction.
Dernière mise à jour
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Résumé
Echinacea has immunostimulant properties in vitro and could theoretically blunt the T-cell depleting effect of rabbit antithymocyte globulin. This might reduce protection against rejection or graft-versus-host disease. Clinical evidence is lacking.
Ce que signifie cette interaction, en termes simples
Antithymocyte globulin rabbit and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Theoretical pharmacodynamic antagonism between herbal immune stimulation and profound T-cell depletion.
Conduite à tenir
Advise transplant patients to avoid echinacea products during and after antithymocyte globulin therapy. Monitor for signs of rejection if the herb has been used.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Echinacea
- Alefacept + Echinacea Modérée
- Antithymocyte globulin equine + Echinacea Modérée
- Azathioprine + Echinacea Modérée
- Basiliximab + Echinacea Modérée
- Cyclosporine + Echinacea Modérée
- Cyclosporin + Echinacea Modérée
Questions fréquentes
Can I take Antithymocyte globulin rabbit with Echinacea?
MediHelp rates the interaction as moderate. Antithymocyte globulin rabbit and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea has immunostimulant properties in vitro and could theoretically blunt the T-cell depleting effect of rabbit antithymocyte globulin. This might reduce protection against rejection or graft-versus-host disease. Clinical evidence is lacking.
How serious is the interaction between Antithymocyte globulin rabbit and Echinacea?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant patients to avoid echinacea products during and after antithymocyte globulin therapy. Monitor for signs of rejection if the herb has been used.
What other medicines interact with Echinacea?
MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Azathioprine. The full list is on the Echinacea page.
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