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Interactions médicamenteuses

Cyclosporine + Echinacea

Gravité: Modérée

Cyclosporine and Echinacea: moderate interaction.

Dernière mise à jour

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Résumé

Echinacea's immunostimulatory activity may theoretically counteract cyclosporine immunosuppression in transplant or autoimmune patients, raising rejection or flare risk. Some data suggest echinacea may also modestly affect CYP3A activity, though the findings are inconsistent.

Ce que signifie cette interaction, en termes simples

Cyclosporine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Low

Pourquoi elle survient

Theoretical pharmacodynamic antagonism by immune stimulation, with possible minor CYP3A modulation.

Conduite à tenir

Advise transplant recipients to avoid echinacea. If used, monitor cyclosporine trough concentrations and graft function.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Cyclosporine with Echinacea?

MediHelp rates the interaction as moderate. Cyclosporine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea's immunostimulatory activity may theoretically counteract cyclosporine immunosuppression in transplant or autoimmune patients, raising rejection or flare risk. Some data suggest echinacea may also modestly affect CYP3A activity, though the findings are inconsistent.

How serious is the interaction between Cyclosporine and Echinacea?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant recipients to avoid echinacea. If used, monitor cyclosporine trough concentrations and graft function.

What other medicines interact with Echinacea?

MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Antithymocyte globulin rabbit. The full list is on the Echinacea page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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