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Interactions médicamenteuses

Aspirin / citric acid / sodium bicarbonate + Ketorolac

Gravité: Contre-indiquée

Aspirin / citric acid / sodium bicarbonate and Ketorolac: contraindicated interaction.

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Résumé

Ketorolac labeling contraindicates use with aspirin and other NSAIDs. The effervescent aspirin product delivers analgesic-dose aspirin, so bleeding, ulcer and renal risks are additive.

Ce que signifie cette interaction, en termes simples

Aspirin / citric acid / sodium bicarbonate and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: High

Pourquoi elle survient

Additive cyclooxygenase inhibition causing GI mucosal injury, platelet inhibition and reduced renal prostaglandins.

Conduite à tenir

Do not use together. Choose a non-NSAID analgesic such as paracetamol instead of one of the agents.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Aspirin / citric acid / sodium bicarbonate with Ketorolac?

MediHelp rates the interaction as contraindicated. Aspirin / citric acid / sodium bicarbonate and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac labeling contraindicates use with aspirin and other NSAIDs. The effervescent aspirin product delivers analgesic-dose aspirin, so bleeding, ulcer and renal risks are additive.

How serious is the interaction between Aspirin / citric acid / sodium bicarbonate and Ketorolac?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Choose a non-NSAID analgesic such as paracetamol instead of one of the agents.

What other medicines interact with Ketorolac?

MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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