Interactions médicamenteuses
Aspirin / citric acid / sodium bicarbonate + Mesalamine
Gravité: Modérée
Aspirin / citric acid / sodium bicarbonate and Mesalamine: moderate interaction.
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Résumé
Mesalamine can rarely cause interstitial nephritis and the aspirin in this effervescent analgesic can reduce renal prostaglandin-dependent perfusion. Together they may increase the risk of kidney injury.
Ce que signifie cette interaction, en termes simples
Aspirin / citric acid / sodium bicarbonate and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Additive nephrotoxicity through salicylate-related renal effects and mesalamine-related interstitial nephritis.
Conduite à tenir
Monitor serum creatinine periodically, especially with frequent aspirin use or renal impairment; prefer paracetamol for analgesia if possible.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Mesalamine
Questions fréquentes
Can I take Aspirin / citric acid / sodium bicarbonate with Mesalamine?
MediHelp rates the interaction as moderate. Aspirin / citric acid / sodium bicarbonate and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine can rarely cause interstitial nephritis and the aspirin in this effervescent analgesic can reduce renal prostaglandin-dependent perfusion. Together they may increase the risk of kidney injury.
How serious is the interaction between Aspirin / citric acid / sodium bicarbonate and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine periodically, especially with frequent aspirin use or renal impairment; prefer paracetamol for analgesia if possible.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
