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Interactions médicamenteuses

Atenolol-chlorthalidone + Timolol

Gravité: Majeure

Atenolol-chlorthalidone and Timolol: major interaction.

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Résumé

Atenolol and timolol are both beta-blockers, so combining them is duplication. This increases bradycardia, hypotension and AV block risk without added benefit.

Ce que signifie cette interaction, en termes simples

Atenolol-chlorthalidone and Timolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Atenolol-chlorthalidone belongs to Cardiovascular; Timolol belongs to Cardiovascular.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive beta-adrenergic receptor blockade (therapeutic duplication).

Conduite à tenir

Avoid combining; use one beta-blocker. If timolol is an eye drop, monitor heart rate as systemic absorption can add to atenolol effects.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Atenolol-chlorthalidone with Timolol?

MediHelp rates the interaction as major. Atenolol-chlorthalidone and Timolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Atenolol and timolol are both beta-blockers, so combining them is duplication. This increases bradycardia, hypotension and AV block risk without added benefit.

How serious is the interaction between Atenolol-chlorthalidone and Timolol?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining; use one beta-blocker. If timolol is an eye drop, monitor heart rate as systemic absorption can add to atenolol effects.

What other medicines interact with Atenolol-chlorthalidone?

MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.

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