Interactions médicamenteuses
Azelaic acid + Urea
Gravité: Mineure
Azelaic acid and Urea: minor interaction.
Dernière mise à jour Sources: US FDA label
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Résumé
Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
Ce que signifie cette interaction, en termes simples
Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Urea belongs to Miscellaneous.
Pourquoi elle survient
Additive local irritation, with urea's keratolytic and hydrating action possibly increasing penetration of azelaic acid.
Conduite à tenir
If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Références
Autres interactions de Azelaic acid
- Azelaic acid + Tretinoin Mineure
Autres interactions de Urea
- Tretinoin + Urea Mineure
Questions fréquentes
Can I take Azelaic acid with Urea?
MediHelp rates the interaction as minor. Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
How serious is the interaction between Azelaic acid and Urea?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Tretinoin. The full list is on the Azelaic acid page.
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