Interactions médicamenteuses
Azelaic acid + Tretinoin
Gravité: Mineure
Azelaic acid and Tretinoin: minor interaction.
Dernière mise à jour Sources: US FDA label
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Résumé
Using both topical agents together can cause additive local irritation such as redness, dryness, burning and peeling. The combination is used deliberately in some acne and hyperpigmentation regimens, and irritation is usually manageable. Patients with sensitive skin or rosacea are most affected.
Ce que signifie cette interaction, en termes simples
Azelaic acid and Tretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Tretinoin belongs to Dermatology.
Pourquoi elle survient
Pharmacodynamic additive local irritation from tretinoin-induced epidermal turnover and the mild irritant effect of azelaic acid.
Conduite à tenir
Apply at different times, for example azelaic acid in the morning and tretinoin at night, or alternate days at the start. Begin with low frequency or strength and use a moisturizer.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Références
- Finacea (azelaic acid) Gel Prescribing Information — FDA Label
- Retin-A (tretinoin) Prescribing Information — FDA Label
Autres interactions de Azelaic acid
- Azelaic acid + Urea Mineure
Autres interactions de Tretinoin
- Doxycycline + Tretinoin Majeure
- Minocycline + Tretinoin Majeure
- Omadacycline + Tretinoin Majeure
- Palovarotene + Tretinoin Majeure
- Sarecycline + Tretinoin Majeure
- Tetracycline + Tretinoin Majeure
Questions fréquentes
Can I take Azelaic acid with Tretinoin?
MediHelp rates the interaction as minor. Azelaic acid and Tretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Using both topical agents together can cause additive local irritation such as redness, dryness, burning and peeling. The combination is used deliberately in some acne and hyperpigmentation regimens, and irritation is usually manageable. Patients with sensitive skin or rosacea are most affected.
How serious is the interaction between Azelaic acid and Tretinoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Apply at different times, for example azelaic acid in the morning and tretinoin at night, or alternate days at the start. Begin with low frequency or strength and use a moisturizer.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Urea. The full list is on the Azelaic acid page.
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