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Interactions médicamenteuses

Bcg vaccine live + Cefuroxime

Gravité: Modérée

Bcg vaccine live and Cefuroxime: moderate interaction.

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Résumé

Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host. Cefuroxime has little expected activity against BCG, so the effect is largely theoretical.

Ce que signifie cette interaction, en termes simples

Bcg vaccine live and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Low

Pourquoi elle survient

Antibacterial activity could reduce replication of the live attenuated organism, though cephalosporin activity against BCG is limited.

Conduite à tenir

Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of cefuroxime.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Bcg vaccine live with Cefuroxime?

MediHelp rates the interaction as moderate. Bcg vaccine live and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Live BCG is a viable bacterium, and an active antibiotic may reduce its viability in the host. Cefuroxime has little expected activity against BCG, so the effect is largely theoretical.

How serious is the interaction between Bcg vaccine live and Cefuroxime?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where timing is flexible, give BCG after the antibiotic course is complete. Do not delay urgent vaccination solely because of cefuroxime.

What other medicines interact with Cefuroxime?

MediHelp also lists interactions of Cefuroxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefuroxime page.

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