Interactions médicamenteuses
Bcg vaccine live + Prednisolone
Gravité: Contre-indiquée
Bcg vaccine live and Prednisolone: contraindicated interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
BCG is a live attenuated mycobacterium that can cause disseminated BCG disease in immunosuppressed patients, and prednisolone may also reduce the response. This is a risk of serious infection.
Ce que signifie cette interaction, en termes simples
Bcg vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Corticosteroid-induced suppression of cell-mediated immunity permits uncontrolled replication of live BCG and reduces vaccine response.
Conduite à tenir
Do not give BCG during immunosuppressive prednisolone therapy; defer until steroids have been stopped for an adequate interval, per local guidance. Assess alternative TB prevention strategies if indicated.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Bcg vaccine live et Prednisolone, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Prednisolone
- Measles mumps and rubella vaccine live + Prednisolone Contre-indiquée
- Measles mumps rubella and varicella vaccine live + Prednisolone Contre-indiquée
- Measles vaccine + Prednisolone Contre-indiquée
- Mifepristone + Prednisolone Contre-indiquée
- Prednisolone + Radium-223 dichloride Contre-indiquée
- Prednisolone + Rubella vaccine Contre-indiquée
Questions fréquentes
Can I take Bcg vaccine live with Prednisolone?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated mycobacterium that can cause disseminated BCG disease in immunosuppressed patients, and prednisolone may also reduce the response. This is a risk of serious infection.
How serious is the interaction between Bcg vaccine live and Prednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during immunosuppressive prednisolone therapy; defer until steroids have been stopped for an adequate interval, per local guidance. Assess alternative TB prevention strategies if indicated.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live, Measles vaccine. The full list is on the Prednisolone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
