Interactions médicamenteuses
Benzhydrocodone / acetaminophen + Cetirizine
Gravité: Modérée
Benzhydrocodone / acetaminophen and Cetirizine: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Benzhydrocodone is an opioid prodrug of hydrocodone, and opioids combined with sedating antihistamines can add to drowsiness and, less commonly, respiratory depression. Cetirizine is less sedating than older antihistamines, so the effect is usually modest.
Ce que signifie cette interaction, en termes simples
Benzhydrocodone / acetaminophen and Cetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Additive CNS depression from opioid mu-receptor agonism and H1 antagonism.
Conduite à tenir
Use the lowest effective opioid dose and monitor for sedation and slowed breathing, especially when starting therapy or raising doses. Counsel patients against alcohol and driving.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Benzhydrocodone / acetaminophen et Cetirizine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.
Autres interactions de Cetirizine
- Acrivastine + Cetirizine Modérée
- Amisulpride + Cetirizine Modérée
- Asenapine + Cetirizine Modérée
- Avapritinib + Cetirizine Modérée
- Brexpiprazole + Cetirizine Modérée
- Brivaracetam + Cetirizine Modérée
Questions fréquentes
Can I take Benzhydrocodone / acetaminophen with Cetirizine?
MediHelp rates the interaction as moderate. Benzhydrocodone / acetaminophen and Cetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benzhydrocodone is an opioid prodrug of hydrocodone, and opioids combined with sedating antihistamines can add to drowsiness and, less commonly, respiratory depression. Cetirizine is less sedating than older antihistamines, so the effect is usually modest.
How serious is the interaction between Benzhydrocodone / acetaminophen and Cetirizine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective opioid dose and monitor for sedation and slowed breathing, especially when starting therapy or raising doses. Counsel patients against alcohol and driving.
What other medicines interact with Cetirizine?
MediHelp also lists interactions of Cetirizine with, for example, Acrivastine, Amisulpride, Asenapine. The full list is on the Cetirizine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
