Interactions médicamenteuses
Betamethasone + Levofloxacin
Gravité: Majeure
Betamethasone and Levofloxacin: major interaction.
Dernière mise à jour
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Résumé
Using a fluoroquinolone together with a systemic corticosteroid increases the risk of tendinitis and tendon rupture, particularly of the Achilles tendon. The risk is higher in older adults and transplant patients.
Ce que signifie cette interaction, en termes simples
Betamethasone and Levofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betamethasone belongs to Endocrine; Levofloxacin belongs to Anti Bacterial.
Pourquoi elle survient
Both drugs have adverse effects on tendon tissue and collagen integrity, and the effects appear to be additive.
Conduite à tenir
Avoid the combination where possible, especially in patients over 60. Stop levofloxacin and rest the limb if tendon pain or swelling develops.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Levofloxacin
- Dronedarone + Levofloxacin Contre-indiquée
- Ibutilide + Levofloxacin Contre-indiquée
- Levofloxacin + Thioridazine Contre-indiquée
- Levofloxacin + Vandetanib Contre-indiquée
- Levofloxacin + Ziprasidone Contre-indiquée
- Adagrasib + Levofloxacin Majeure
Autres interactions de Betamethasone
- Betamethasone + Ciprofloxacin Majeure
- Betamethasone + Gemifloxacin Majeure
- Betamethasone + Moxifloxacin Majeure
- Betamethasone + Ofloxacin Majeure
- Alogliptin-metformin + Betamethasone Modérée
- Atracurium + Betamethasone Modérée
Questions fréquentes
Can I take Betamethasone with Levofloxacin?
MediHelp rates the interaction as major. Betamethasone and Levofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Using a fluoroquinolone together with a systemic corticosteroid increases the risk of tendinitis and tendon rupture, particularly of the Achilles tendon. The risk is higher in older adults and transplant patients.
How serious is the interaction between Betamethasone and Levofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, especially in patients over 60. Stop levofloxacin and rest the limb if tendon pain or swelling develops.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.