Interactions médicamenteuses
Betrixaban + Tirofiban
Gravité: Majeure
Betrixaban and Tirofiban: major interaction.
Dernière mise à jour
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Résumé
Combining a glycoprotein IIb/IIIa inhibitor with a factor Xa inhibitor raises the risk of serious bleeding. Both agents impair hemostasis through different pathways.
Ce que signifie cette interaction, en termes simples
Betrixaban and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive pharmacodynamic effects: factor Xa inhibition by betrixaban plus inhibition of platelet aggregation by tirofiban.
Conduite à tenir
Avoid the combination where possible, or limit its duration and monitor closely for bleeding and falls in hemoglobin. Reassess the need for both agents daily.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Tirofiban
- Abrocitinib + Tirofiban Majeure
- Acalabrutinib + Tirofiban Majeure
- Acetylsalicylic acid + Tirofiban Majeure
- Antithrombin alfa + Tirofiban Majeure
- Antithrombin iii + Tirofiban Majeure
- Apixaban + Tirofiban Majeure
Questions fréquentes
Can I take Betrixaban with Tirofiban?
MediHelp rates the interaction as major. Betrixaban and Tirofiban can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining a glycoprotein IIb/IIIa inhibitor with a factor Xa inhibitor raises the risk of serious bleeding. Both agents impair hemostasis through different pathways.
How serious is the interaction between Betrixaban and Tirofiban?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, or limit its duration and monitor closely for bleeding and falls in hemoglobin. Reassess the need for both agents daily.
What other medicines interact with Tirofiban?
MediHelp also lists interactions of Tirofiban with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Tirofiban page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
