Interactions médicamenteuses
Bleomycin + Dengue vaccine
Gravité: Majeure
Bleomycin and Dengue vaccine: major interaction.
Dernière mise à jour
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Résumé
Dengue vaccine is live attenuated, and cytotoxic chemotherapy can weaken immune control of the vaccine virus. This may cause vaccine-related infection and a poor immune response.
Ce que signifie cette interaction, en termes simples
Bleomycin and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Chemotherapy-induced immunosuppression impairs vaccine response and permits replication of live vaccine virus.
Conduite à tenir
Avoid live vaccines during chemotherapy and defer until immune recovery per local guidance. Obtain specialist advice if vaccination is urgently needed.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Bleomycin
- Adenovirus types 4 and 7 live + Bleomycin Contre-indiquée
- Bleomycin + Brentuximab Contre-indiquée
- Bleomycin + Brentuximab vedotin Contre-indiquée
- Bleomycin + Trastuzumab deruxtecan Majeure
- Bleomycin + Cholera vaccine Modérée
- Bleomycin + Ethotoin Modérée
Questions fréquentes
Can I take Bleomycin with Dengue vaccine?
MediHelp rates the interaction as major. Bleomycin and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is live attenuated, and cytotoxic chemotherapy can weaken immune control of the vaccine virus. This may cause vaccine-related infection and a poor immune response.
How serious is the interaction between Bleomycin and Dengue vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and defer until immune recovery per local guidance. Obtain specialist advice if vaccination is urgently needed.
What other medicines interact with Bleomycin?
MediHelp also lists interactions of Bleomycin with, for example, Adenovirus types 4 and 7 live, Brentuximab, Brentuximab vedotin. The full list is on the Bleomycin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
