Interactions médicamenteuses
Buprenorphine long-acting + Esketamine
Gravité: Majeure
Buprenorphine long-acting and Esketamine: major interaction.
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Résumé
Esketamine and opioids can each cause sedation and dissociation, and together they may increase CNS and respiratory depression. Long-acting buprenorphine provides continuous exposure, so effects can overlap with each esketamine session.
Ce que signifie cette interaction, en termes simples
Buprenorphine long-acting and Esketamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive CNS and respiratory depression.
Conduite à tenir
Monitor sedation, oxygen saturation, and breathing throughout the post-dose observation period. Use only when alternatives are inadequate.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Esketamine
- Alfentanil + Esketamine Majeure
- Amobarbital + Esketamine Majeure
- Belladonna and opium + Esketamine Majeure
- Benzhydrocodone / acetaminophen + Esketamine Majeure
- Buprenorphine transdermal + Esketamine Majeure
- Buprenorphine + Esketamine Majeure
Questions fréquentes
Can I take Buprenorphine long-acting with Esketamine?
MediHelp rates the interaction as major. Buprenorphine long-acting and Esketamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Esketamine and opioids can each cause sedation and dissociation, and together they may increase CNS and respiratory depression. Long-acting buprenorphine provides continuous exposure, so effects can overlap with each esketamine session.
How serious is the interaction between Buprenorphine long-acting and Esketamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation, oxygen saturation, and breathing throughout the post-dose observation period. Use only when alternatives are inadequate.
What other medicines interact with Esketamine?
MediHelp also lists interactions of Esketamine with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Esketamine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
