Interactions médicamenteuses
Carbamazepine + Vitamin B12
Gravité: Mineure
Carbamazepine and Vitamin B12: minor interaction.
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Résumé
Long-term carbamazepine has been associated with lower serum B12 in some observational studies. The change is usually small and rarely leads to clinical deficiency, though it may matter in patients with other risk factors.
Ce que signifie cette interaction, en termes simples
Carbamazepine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbamazepine belongs to Central Nervous System; Vitamin B12 belongs to Gastrointestinal Tract.
Pourquoi elle survient
Mechanism is not established; enzyme induction or altered B12 handling has been proposed.
Conduite à tenir
Check B12 levels if the patient on long-term carbamazepine has anemia, neuropathy or cognitive symptoms. Supplement only if deficiency is confirmed.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Vitamin B12
- Chloramphenicol + Vitamin B12 Modérée
- Dichlorphenamide + Vitamin B12 Modérée
- Metformin + Vitamin B12 Modérée
- Neomycin po + Vitamin B12 Modérée
- Aspirin / citric acid / sodium bicarbonate + Vitamin B12 Mineure
- Aspirin + Vitamin B12 Mineure
Autres interactions de Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contre-indiquée
- Cabotegravir + Carbamazepine Contre-indiquée
- Carbamazepine + Delamanid Contre-indiquée
- Carbamazepine + Dienogest / estradiol valerate Contre-indiquée
- Carbamazepine + Doravirine Contre-indiquée
- Carbamazepine + Elbasvir / grazoprevir Contre-indiquée
Questions fréquentes
Can I take Carbamazepine with Vitamin B12?
MediHelp rates the interaction as minor. Carbamazepine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Long-term carbamazepine has been associated with lower serum B12 in some observational studies. The change is usually small and rarely leads to clinical deficiency, though it may matter in patients with other risk factors.
How serious is the interaction between Carbamazepine and Vitamin B12?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check B12 levels if the patient on long-term carbamazepine has anemia, neuropathy or cognitive symptoms. Supplement only if deficiency is confirmed.
What other medicines interact with Vitamin B12?
MediHelp also lists interactions of Vitamin B12 with, for example, Chloramphenicol, Dichlorphenamide, Metformin. The full list is on the Vitamin B12 page.
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