Interactions médicamenteuses
Cefadroxil + Mycophenolate
Gravité: Modérée
Cefadroxil and Mycophenolate: moderate interaction.
Dernière mise à jour
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Résumé
Some antibiotics, including cephalosporins, have been associated with lower mycophenolic acid exposure, probably by reducing gut bacteria that deconjugate the glucuronide and allow its reabsorption. The legacy renal competition explanation is not well supported. Reduced exposure could weaken immunosuppression.
Ce que signifie cette interaction, en termes simples
Cefadroxil and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Probable reduction of enterohepatic recirculation of mycophenolic acid glucuronide due to gut flora changes.
Conduite à tenir
Watch for signs of graft rejection or reduced immunosuppression during and after the antibiotic course. Consider mycophenolic acid level monitoring where available.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefadroxil
- Amikacin + Cefadroxil Modérée
- Avelumab + Cefadroxil Modérée
- Balstilimab + Cefadroxil Modérée
- Bcg vaccine live + Cefadroxil Modérée
- Cefadroxil + Cholera vaccine Modérée
- Cefadroxil + Gentamicin Modérée
Questions fréquentes
Can I take Cefadroxil with Mycophenolate?
MediHelp rates the interaction as moderate. Cefadroxil and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Some antibiotics, including cephalosporins, have been associated with lower mycophenolic acid exposure, probably by reducing gut bacteria that deconjugate the glucuronide and allow its reabsorption. The legacy renal competition explanation is not well supported. Reduced exposure could weaken immunosuppression.
How serious is the interaction between Cefadroxil and Mycophenolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Watch for signs of graft rejection or reduced immunosuppression during and after the antibiotic course. Consider mycophenolic acid level monitoring where available.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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