Interactions médicamenteuses
Cefadroxil + Neomycin po
Gravité: Modérée
Cefadroxil and Neomycin po: moderate interaction.
Dernière mise à jour
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Résumé
Oral neomycin is poorly absorbed, but systemic absorption can occur with impaired gut mucosa or renal impairment, and it is nephrotoxic and ototoxic. Combined with cephalosporins, additive kidney injury has been suggested. Cefadroxil itself is only weakly nephrotoxic.
Ce que signifie cette interaction, en termes simples
Cefadroxil and Neomycin po can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Potential additive nephrotoxicity from systemically absorbed neomycin with reduced renal clearance of both drugs.
Conduite à tenir
Monitor renal function, especially with renal impairment or prolonged neomycin use. Adjust cefadroxil dose to creatinine clearance.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Cefadroxil
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- Bcg vaccine live + Cefadroxil Modérée
- Cefadroxil + Cholera vaccine Modérée
- Cefadroxil + Gentamicin Modérée
Questions fréquentes
Can I take Cefadroxil with Neomycin po?
MediHelp rates the interaction as moderate. Cefadroxil and Neomycin po can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral neomycin is poorly absorbed, but systemic absorption can occur with impaired gut mucosa or renal impairment, and it is nephrotoxic and ototoxic. Combined with cephalosporins, additive kidney injury has been suggested. Cefadroxil itself is only weakly nephrotoxic.
How serious is the interaction between Cefadroxil and Neomycin po?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, especially with renal impairment or prolonged neomycin use. Adjust cefadroxil dose to creatinine clearance.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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