Interactions médicamenteuses
Cisatracurium + Fentanyl intranasal
Gravité: Majeure
Cisatracurium and Fentanyl intranasal: major interaction.
Dernière mise à jour
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Résumé
Fentanyl causes respiratory depression, sedation and hypotension, and these effects add to those of a neuromuscular blocker when ventilation is inadequate. Cisatracurium is given only with ventilatory support, but residual blockade plus opioid effect can delay safe recovery.
Ce que signifie cette interaction, en termes simples
Cisatracurium and Fentanyl intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive respiratory depression from central opioid effect and peripheral neuromuscular blockade.
Conduite à tenir
Use only in settings with airway and ventilatory support and monitor neuromuscular blockade, respiration and blood pressure. Reduce doses as needed.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Cisatracurium
Questions fréquentes
Can I take Cisatracurium with Fentanyl intranasal?
MediHelp rates the interaction as major. Cisatracurium and Fentanyl intranasal can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fentanyl causes respiratory depression, sedation and hypotension, and these effects add to those of a neuromuscular blocker when ventilation is inadequate. Cisatracurium is given only with ventilatory support, but residual blockade plus opioid effect can delay safe recovery.
How serious is the interaction between Cisatracurium and Fentanyl intranasal?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only in settings with airway and ventilatory support and monitor neuromuscular blockade, respiration and blood pressure. Reduce doses as needed.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
