Interactions médicamenteuses
Capreomycin + Cisatracurium
Gravité: Majeure
Capreomycin and Cisatracurium: major interaction.
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Résumé
Capreomycin has its own neuromuscular blocking activity and can potentiate and prolong the effect of cisatracurium. This may result in prolonged paralysis and respiratory failure.
Ce que signifie cette interaction, en termes simples
Capreomycin and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive nondepolarizing-type neuromuscular blockade from capreomycin at the neuromuscular junction.
Conduite à tenir
Avoid if possible; otherwise reduce the cisatracurium dose and monitor with train-of-four, with ventilatory support available until full recovery.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Cisatracurium
Questions fréquentes
Can I take Capreomycin with Cisatracurium?
MediHelp rates the interaction as major. Capreomycin and Cisatracurium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has its own neuromuscular blocking activity and can potentiate and prolong the effect of cisatracurium. This may result in prolonged paralysis and respiratory failure.
How serious is the interaction between Capreomycin and Cisatracurium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise reduce the cisatracurium dose and monitor with train-of-four, with ventilatory support available until full recovery.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
