Interactions médicamenteuses
Cyclizine + Henbane
Gravité: Majeure
Cyclizine and Henbane: major interaction.
Dernière mise à jour
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Résumé
Henbane contains the antimuscarinic alkaloids hyoscyamine and scopolamine. Together with cyclizine, anticholinergic effects such as dry mouth, tachycardia, urinary retention, confusion and hyperthermia can be intensified, with toxicity possible given the variable alkaloid content.
Ce que signifie cette interaction, en termes simples
Cyclizine and Henbane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive muscarinic receptor antagonism.
Conduite à tenir
Avoid using henbane with cyclizine. If exposure has occurred, monitor for anticholinergic toxicity and treat supportively.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Cyclizine
- Calcium / magnesium / potassium / sodium oxybates + Cyclizine Majeure
- Cyclizine + Sodium oxybate Majeure
- Abobotulinumtoxina + Cyclizine Modérée
- Alfentanil + Cyclizine Modérée
- Alprazolam + Cyclizine Modérée
- Amantadine + Cyclizine Modérée
Questions fréquentes
Can I take Cyclizine with Henbane?
MediHelp rates the interaction as major. Cyclizine and Henbane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Henbane contains the antimuscarinic alkaloids hyoscyamine and scopolamine. Together with cyclizine, anticholinergic effects such as dry mouth, tachycardia, urinary retention, confusion and hyperthermia can be intensified, with toxicity possible given the variable alkaloid content.
How serious is the interaction between Cyclizine and Henbane?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using henbane with cyclizine. If exposure has occurred, monitor for anticholinergic toxicity and treat supportively.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Abobotulinumtoxina. The full list is on the Cyclizine page.
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