Interactions médicamenteuses
Dengue vaccine + Epirubicin
Gravité: Majeure
Dengue vaccine and Epirubicin: major interaction.
Dernière mise à jour
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Résumé
Dengue vaccine is a live attenuated vaccine. In patients receiving cytotoxic chemotherapy, the immune response may be blunted and the vaccine virus may replicate excessively, causing disease.
Ce que signifie cette interaction, en termes simples
Dengue vaccine and Epirubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Chemotherapy-induced immunosuppression reduces vaccine response and permits uncontrolled replication of live vaccine virus.
Conduite à tenir
Avoid live vaccines during chemotherapy and give them only after immune recovery, typically at least three months after treatment ends per local guidance. Seek specialist advice if vaccination is needed.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Epirubicin
- Adenovirus types 4 and 7 live + Epirubicin Contre-indiquée
- Belatacept + Epirubicin Majeure
- Cimetidine + Epirubicin Majeure
- Deferiprone + Epirubicin Majeure
- Epirubicin + Etrasimod Majeure
- Epirubicin + Fingolimod Majeure
Questions fréquentes
Can I take Dengue vaccine with Epirubicin?
MediHelp rates the interaction as major. Dengue vaccine and Epirubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is a live attenuated vaccine. In patients receiving cytotoxic chemotherapy, the immune response may be blunted and the vaccine virus may replicate excessively, causing disease.
How serious is the interaction between Dengue vaccine and Epirubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and give them only after immune recovery, typically at least three months after treatment ends per local guidance. Seek specialist advice if vaccination is needed.
What other medicines interact with Epirubicin?
MediHelp also lists interactions of Epirubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cimetidine. The full list is on the Epirubicin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
