Interactions médicamenteuses
Dobutamine + Methylergonovine
Gravité: Majeure
Dobutamine and Methylergonovine: major interaction.
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Résumé
Methylergonovine is a potent uterine and vascular constrictor that can raise blood pressure and cause vasospasm. Dobutamine adds adrenergic cardiovascular stimulation, so hypertension and ischemia are more likely. Severe hypertension has been reported with ergot alkaloids and sympathomimetics.
Ce que signifie cette interaction, en termes simples
Dobutamine and Methylergonovine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive vasoconstriction and cardiovascular stimulation.
Conduite à tenir
Avoid the combination where alternatives exist, for example other uterotonics in postpartum hemorrhage. If both are required, monitor blood pressure continuously and treat hypertension promptly.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Dobutamine
- Budesonide-formoterol + Dobutamine Majeure
- Dihydroergotamine intranasal + Dobutamine Majeure
- Dihydroergotamine + Dobutamine Majeure
- Dobutamine + Ergotamine Majeure
- Dobutamine + Ether Majeure
- Dobutamine + Isocarboxazid Majeure
Questions fréquentes
Can I take Dobutamine with Methylergonovine?
MediHelp rates the interaction as major. Dobutamine and Methylergonovine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Methylergonovine is a potent uterine and vascular constrictor that can raise blood pressure and cause vasospasm. Dobutamine adds adrenergic cardiovascular stimulation, so hypertension and ischemia are more likely. Severe hypertension has been reported with ergot alkaloids and sympathomimetics.
How serious is the interaction between Dobutamine and Methylergonovine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where alternatives exist, for example other uterotonics in postpartum hemorrhage. If both are required, monitor blood pressure continuously and treat hypertension promptly.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
